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acute ischaemic stroke

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116218
    Amelparib

    JPI-289

    		 PARP Cardiovascular Disease Neurological Disease
    Amelparib is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50 =18.5 nmol/L) and cellular PAR formation (IC50 =10.7 nmol/L) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke .
    Amelparib
  • HY-116218C
    Amelparib hydrochloride

    JPI-289 hydrochloride

    		 PARP Cardiovascular Disease Neurological Disease
    Amelparib (JPI-289) hydrochloride is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib hydrochloride inhibits PARP-1 activity (IC50 = 18.5 nM) and cellular PAR formation (IC50 = 10.7 nM). Amelparib hydrochloride is a potential neuroprotective agent. Amelparib hydrochloride has the potential for the research of acute ischaemic stroke .
    Amelparib hydrochloride
  • HY-W273690
    Pentifylline

    1-Hexyltheobromine; Hexyltheobromine

    		 Others Cardiovascular Disease
    Pentifylline is a vasodilator. Pentifylline inhibits platelet aggregation and thromboxane A2 synthesis, decrease the release of free radicals. Pentifylline has the potential for the research of acute ischaemic stroke .
    Pentifylline
  • HY-10679A
    PF-03049423

    		Phosphodiesterase (PDE) Neurological Disease
    PF-03049423 (Compound PF-5) is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50 of about 0.2 nM for rat and human platelet enzyme. PF-03049423 can be used for the research of acute ischaemic stroke .
    PF-03049423
  • HY-10679
    PF-03049423 free base

    		Phosphodiesterase (PDE) Neurological Disease
    PF-03049423 (Compound PF-5) free base is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50 of about 0.2 nM for rat and human platelet enzyme. PF-03049423 free base can be used for the research of acute ischaemic stroke .
    PF-03049423 free base
  • HY-108845
    Tenecteplase

    TNK-tPA

    		 Others Metabolic Disease
    Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase (TNK-tPA) can be used for acute ischaemic stroke diseases research .
    Tenecteplase

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